Oral leukoplakia: Diagnosis and treatment

نویسندگان

  • Christian Godballe Professor, Department of ORL-Head and Neck Surgery, Odense University Hospital, Odense, Denmark
  • Jens Ahm Sørensen Professor, Department of Plastic and Reconstructive Surgery, Odense University Hospital, Odense, Denmark
  • Marie Kjaergaard Larsen Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark
  • Torben Henrik Thygesen Associate Professor, Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark
چکیده مقاله:

BACKGROUND AND AIM: Oral leukoplakia (OL) is a common premalignant lesion. The possible benefits of specific interventions in preventing a malignant transformation of OL are not well understood. This review assesses different invasive treatment techniques for OL and evaluate the optimal treatment possibilities.METHODS: A Medline (PubMed) search was conducted and heterogeneity between the studies was found, e.g., with regard to the OL lesions, patient groups, follow-up time, and definition of recurrence.RESULTS: The recurrence and malignant transformation rate after the different treatment methods were evaluated. The mean overall recurrence rate varied with the treatment method.CONCLUSION: A surgical treatment appears to decrease the risk of transformation but does not fully eliminate it. Follow-up should be done regardless of the surgical treatment.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Oral leukoplakia and erythroplakia: a protocol for diagnosis and management

1 Santiago de Compostela University, School of Medicine and Dentistry, Special Needs Unit, Santiago de Compostela, Spain 2 Tel-Aviv University, School of Dental Medicine, Tel-Aviv, Israel 3 Griffith Health Institute, Gold Coast Campus, Queensland, Australia 4 University of Copenhagen, Department of Oral Medicine, Section of Oral Pathology & Medicine, Copenhagen, Denmark 5 University of Parma, O...

متن کامل

Oral hairy leukoplakia: clinicopathologic features, pathogenesis, diagnosis, and clinical significance.

Oral hairy leukoplakia (OHL) is a lesion frequently, although not exclusively, observed in patients infected by human immunodeficiency viruses (HIV). OHL is clinically characterized by bilateral, often elevated, white patches of the lateral borders and dorsum of the tongue. Histologically, there is profound acanthosis, sometimes with koilocytic changes, and a lack of a notable inflammatory infi...

متن کامل

Efficacy of oral lycopene in the treatment of oral leukoplakia.

This study evaluates the efficacy of lycopene in the treatment of oral leukoplakia and compares two different doses with a placebo. Fifty-eight clinically and histologically diagnosed patients of oral leukoplakia were selected for the study. They were randomly divided into three groups. Group A: (n = 20; 8 mg lycopene/day), Group B: (n = 20; 4 mg lycopene/day) and Group C: (n = 18; placebo). Th...

متن کامل

Proliferative verrucous leukoplakia misdiagnosed as oral leukoplakia

Correct diagnosis of white lesions of the oral cavity is sometimes difficult, because some oral white lesions behave differently and tend to change their appearance with time. Clinicians often wrongly diagnose such lesions as oral leukoplakias and treat simply. Lesions recur and turn malignant. Proliferative verrucous leukoplakia (PVL) is a distinct form of oral leukoplakia characterized by a h...

متن کامل

A clinical diagnosis of oral leukoplakia; A guide for dentists

BACKGROUND In view of the many white or predominantly white lesions of the oral mucosa it is a challenge for dentists to clinically identify a leukoplakia, being a potentially (pre)malignant lesion. MATERIAL AND METHODS Based on the available literature and experience of the authors the parameters of a clinical diagnosis of oral leukoplakia have been studied. RESULTS A guide has been presen...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 5  شماره 2

صفحات  57- 69

تاریخ انتشار 2016-05-28

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023